CD8-Positive T-Cell Leukoencephalitis With Astrocytopathy Clinically Presenting as Neuromyelitis Optica
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چکیده
منابع مشابه
Neuromyelitis Optica Spectrum Disorder Presenting with Pseudoathetosis
Dear Editor, Pseudoathetosis is a movement disorder that is characterized by involuntary, slow, and writhing movements. It can develop from lesions at all levels of proprioceptive sensory pathways, including the posterior column of the spinal cord, parietal cortex, thalamus, and peripheral nerves.1,2 Various conditions that involve the posterior column have been reported to cause spinal pseudoa...
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A 33-year-old African-American woman recently diagnosed with severe idiopathic gastroparesis was readmitted for hypoxic respiratory failure secondary to aspiration pneumonia. A fiber-optic endoscopic evaluation of swallow study revealed severe pharyngeal dysphagia. Brain magnetic resonance imaging showed an ill-defined lesion in the posterior aspect of the medulla concerning for a demyelinating...
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BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...
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The distribution of neuromyelitis optica (NMO)-characteristic brain lesions corresponds to sites of high aquaporin-4 (AQP4) expression, and the brainstem and hypothalamus lesions that express high levels of AQP4 protein are relatively characteristic of NMO. The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is one of the important causes of hyponatremia and results from an abn...
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BACKGROUND Multiple sclerosis (MS) and neuromyelitis optica (NMO) occasionally have an extremely aggressive and debilitating disease course; however, its molecular basis is unknown. This study aimed to determine a relationship between connexin (Cx) pathology and disease aggressiveness in Asian patients with MS and NMO. METHODS/PRINCIPAL FINDINGS Samples included 11 autopsied cases with NMO an...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2017
ISSN: 0022-3069,1554-6578
DOI: 10.1093/jnen/nlx015